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BIOCOX

Cinnamomum verum, Oregano, Tea tree

Supports during coccidiosis
Helps reduce the severity of Eimeria spp.
Helps reduce the economic effects of Eimeria spp. invasion
Supports natural immunity

Product type: liquid

Available capacity: 1L, 2L, 5L

How does BIOCOX work?

BIOCOX effectively supports organisms in the fight against coccidiosis, by directly acting on protozoa and influencing the local immunity of birds. It can be used prophylactically and also when coccidiosis occurs on the farm, helping to reduce economic losses related to the course of infection. BIOCOX ingredients limit the development of coccidiosis by influencing the physiological processes of protozoa, including: disrupting enzyme function, integrity of cellular structures, and the life cycle of parasites. They support the immune system in the fight against parasites. They also increase birds’ appetite and digestion processes, which are extremely important due to the risk of a decrease in performance during infection. In addition, BIOCOX ingredients present beneficial effects on the processes of bile formation and secretion, which is the body’s natural antiparasitic weapon in the digestive tract.

Recommended support during:

coccidiosis and co-infection caused by anaerobic bacteria
histomonosis

Expected results

Supports weight gain

How to dose BIOCOX?

How to dose Biocox?
Standard: 500 ml/1000 l of drinking water, in ½ of the daily water drunk, for 3-5 days
In case of very severe symptoms: 1000 ml/1000 l of drinking water, in ½ of the daily water drunk, 3-5 days
Depending on the clinical condition of the birds: 1000 ml/1000 l of drinking water, in ½ of the daily water drunk, for 3-5 days.

BIOCOX we recommend use with the following products:

Support during	Supportive product	Why provide a supporting product?	How to dose a supporting product together with Biocox?
Coccidiosis	SALIVET PLUS	To support in times of inflammation	250-500 ml/1000 l of drinking water, in the second ½ of the daily water drunk, 5-7 days Do not use together (in same water) with Biocox
	BIOLAX PLUS	In case of diarrhea caused by coccidiosis, in order to limit it	500-1000 ml/1000 l of drinking water, in the second ½ of the daily water drunk, 3-5 days Do not use together (in same water) with Biocox
Coccidiosis and co-infection caused by anaerobic bacteria	CLOSTRIC	To reduce infection caused by anaerobic bacteria	500 ml/1000 l of drinking water, in the second ½ of the daily water drunk, 3-5 days Do not use together (in same water) with Biocox
	MULTI ACTIV	To support the pH balance of the digestive tract contents and enhance the effect	500-1000 ml/1000 l of drinking water, in ½ of the daily water drunk, 3-5 days It can be used together (in same water) with CLOSTRIC
Histomonasis	BOOSTER	To support immunity	250-500 ml/1000 l of drinking water, in ½ of the daily water drunk, 3-5 days

BIOCOX supportive products:

Reduces the problem of "wet litter", helps reduce the symptoms of diarrhea, supports the body in the fight against the causes and symptoms of indigestion

BIOLAX PLUS

Supports the animal body during periods of indigestion or diarrhea

Increases the intensity of the immune response, supports the regeneration of mucous membranes, supports the production of T lymphocytes and IgA immunoglobulins, provides support during periods of decreased immunity and increased risk of viral infections

BOOSTER

Supports animals during preventive vaccinations

Restores the balance of the digestive tract after an infection, stimulates the secretion of digestive enzymes, stimulates digestion and improves the absorption of feed ingredients

CLOSTRIC

Reduces the occurrence of Clostridium spp. infections.

Supports digestive processes, improves feed intake and daily body weight gain, helps reduce the occurrence of diarrhea and indigestion

MULTI ACTIV

Optimizes the pH of the digestive tract

Bestseller

Contains 9 active substances, supports in times of inflammation and pain, supports the condition of birds during the period of infection

SALIVET PLUS

Contains natural salicylates

I. BIRDS

Chicken broiler ROSS 308, 40 000 pcs., henhouse K3, Podlaskie voivodeship

II. CASE DESCRIPTION

III. ANATOMOPATHOLOGICAL EXAMINATION

Anatomopathological examination revealed:

white, punctate lesions in the duodenum (Fig. 1)
local petechiae within the intestinal epithelium (Fig. 2)
loosening of the mucous membrane of the duodenum and jejunum
mucous intestinal content

Fig. 1 – white, punctate lesions in the duodenum

Fig. 2 – local petechiae within the intestinal epithelium

IV. FAECAL PARASITOLOGICAL EXAMINATION

Quantitative parasitological examination, McMaster chamber method according to Raynaud.

On day 25, the sample examined showed: 91,000 oocysts/1 g of faeces

V. DIAGNOSIS

INWAZJA EIMERIA SPP.

VI. RECOMMENDATIONS

BIOCOX in a dose of 500 ml/1000 l of drinking water, in ½ of the daily water drunk, for 3 days (from day 25 to 27)

VII. EFFECTS

On the 27th day, the herd was reassessed and the anatomopathological and parasitological examinations were repeated. A clear reduction in indigestion was observed (less feed was observed in stool), the herd is more balanced than before the start of the therapy. The anatomopathological examination did not reveal changes characteristic of Eimeria spp. invasion.

Parasitological examination revealed: 22,000 oocysts/1 g faeces.

VIII. SUMMARY

After treatment, the herd stabilized. There were no anatomopathological changes characteristic of Eimeria spp. invasion in the intestines. There was a significant reduction in the number of oocysts in 1 g of faeces (data presented in Table 1). After the therapy, the herd stabilized. There were no anatomopathological changes characteristic of Eimeria spp. invasion in the intestines. There was a significant reduction in the number of oocysts in 1 g of stool (data presented in Table 1). At the end of the production cycle, the birds compensated for the loss of body weight gain caused by the infection. The average body weight at the end of the flush was 2.98 kg (for a cycle duration of 40.8 days), the feed conversion ratio was 1.62. In the summary of production parameters, despite the occurrence of coccidiosis, this flush was successful – EWW coefficient 429.5.

Table 1. Number of oocysts in 1 g of stool.

I. BIRDS

Chicken broiler ROSS 308, 25 000 pcs., Podlaskie voivodship

II. CASE DESCRIPTION

On the 26th day of the birds’ life, a slight diversification of the flock was observed and the number of daily mortality increased to 40 birds per day.

III. ANATOMOPATHOLOGICAL EXAMINATION

Anatomopathological examination revealed changes in the duodenum:

mucosal distension (Fig. 1)
presence of mucus in the contents and on the mucosa (Fig. 1)
numerous white spots on the mucosa (Fig. 1)
petechiae of varying degrees of severity (Fig. 2)

Fig. 1

Fig. 2

IV. FAECAL PARASITOLOGICAL EXAMINATION

Quantitative parasitological examination, McMaster chamber method according to Raynaud.

On day 26, 56,400 oocysts/1 g of faeces were found in the sample examined

V. DIAGNOSIS

EIMERIA SPP INVASION. (most probably E. acervulina)

VI. RECOMMENDATIONS

BIOCOX in a dose of 1000 ml/1000 l of drinking water, continuously administered for 5 days

VII. EFFECT

On day 36, the herd was reassessed. The anatomopathological and parasitological examination was repeated.

After treatment, the herd stabilized (Fig. 3) and the number of daily mortality decreased (Table 1). Anatomopathological examination did not reveal any changes characteristic of Eimeria spp. invasion (Fig. 4 and 5). In one case, petechiae and swelling of the jejunal mucosa were found (Fig. 6).

On day 36, parasitological examination revealed 1,300 and 1,600 oocysts/1 g of faeces in two samples.

Fig. 3

Fig. 4

Fig. 5

Fig. 6

VIII. SUMMARY

After using Biocox, a reduction in the number of mortality was observed (Table 1), the herd became more stable, the intensity of anatomical changes in the duodenum was reduced, and the number of oocysts in 1 g of stool was significantly reduced (Table 2).

Table 1 Daily mortality of birds.

Table 2 Number of oocysts in 1 g of faeces.

Manufactured using ALL – IN technology

All-In Technology is a patented technology for obtaining and standardizing herbal preparations. Each production stage is subject to strict control, from the selection of raw materials, through extraction, to the creation of the finished product.

Key features of patented all-in technology:

High product activity throughout its shelf life

Constant product activity along the entire length of the drinking line

Constant level of active ingredients

Less susceptibility to external factors

Low dosage, high efficiency

Elimination of inactive substances

Composition in 1L/1kg

FEED MATERIALS:
propylene glycol (13.11.1), glycerin (13.8.2)

FEED ADDITIVES:
Sensory additives: Flavoring substances: Mixture of flavoring substances;
Dietary additives: Vitamins: Vitamin B2 (riboflavin phosphate in the form of sodium salt) (3a826) – 400 mg;
Technological additives: Emulsifiers: Polyoxyethylene castor oil (E484) – 415,000 mg